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Depression induced or cured within 10 seconds in rats by turning on or off neurons that release dopamine in the ventral tegmental area of the brain with the help of optogenetics (previously changing neurons to make them be turned on or off by focusing light on them). 10 seconds is shorter than the time that antidepressants usually take to work, which is some weeks. Treatment with magnesium may work within one week, and could be combined for best results with vitamin D, vitamin B12, folic acid, and omega-3.

via Stimulating dopamine-releasing neurons in the ventral tegmental area immediately extinguishes depression in mice. | MIT Technology Review.

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